PhenotypicIn VivoScreening to Identify New, Unpredicted Indications for Existing Drugs and Drug Candidates
Michael S. Saporito, Christopher A. Lipinski, Andrew G. Reaume · 2012
This chapter contains sections titled: Introduction Settings for In Vivo Drug Repositioning In Vivo Models Advantages of Compound Screening in Phenotypic In Vivo Models Design of an Optimal Drug Repositioning Platform Results from Phenotypic Screening Studies Compound Selection for Drug Repositioning Exclusivity Strategies for Repositioned Drugs Identified by Phenotypic Screening Summary References