In VitroADME Profiling and Pharmacokinetic Screening in Drug Discovery
Daniel B. Kassel · 2010
This chapter contains sections titled: Introduction ADME Screening in Drug Discovery In Vitro Absorption and Permeability Screening Cytochrome P450 Metabolism Studies Higher-Throughput Analytical Methods to Support ADME Evaluation Automated Data Processing is Instrumental in Achieving High-Throughput ADME “All-in-One” Metabolic Stability and Metabolite Detection Studies High-Throughput Pharmacokinetic Screening Conclusions