Cheminformatics Approaches to Fragment‐based Lead Discovery
Tudor Ionel Oprea, Jeffrey M. Blaney · Methods and principles in medicinal chemistry · 2006
This chapter contains sections titled: Introduction The Chemical Space of Small Molecules (Under 300 a.m.u.) The Concept of Lead-likeness The Fragment-based Approach in Lead Discovery Literature-based Identification of Fragments: A Practical Example Conclusions Acknowledgments References