197 Combination of e-pharmacophore modeling, multiple docking strategies and molecular dynamic simulations to discover of novel antagonists of BACE1
N. S. Pradeep, Manne Munikumar, Sandeep Swargam, Kanipakam Hema, Sudheer Kumar Katari, Amineni Umamaheswari · Journal of Biomolecular Structure and Dynamics · 2015
Beta-site amyloid precursor protein cleaving enzyme (BACE1 or β-secretase), an aspartic protease responsible for ramping up of Aβ-40/42 peptide fragments by cleaving APP that conciliate for the pro...