Gene specific co-regulation discovery from gene microarray data
Ji Zhang, Qing Huo Liu, Kai Xu, Paulo de Souza · 2008
The problem of gene specific co-regulation discovery is to identify, for a particular gene of interest, called target gene, its strongly co-regulated genes and the condition subsets where such strong gene co-regulations are observed. In this paper, we propose an efficient method for finding gene-specific co-regulations using genetic algorithm (GA). Compared with the previous method, our method is anticipated to achieve a notably improved efficiency by using a number of performance boost strategies.