Biological and Chemistry Assays Available During Drug Discovery And Developability Assessment
Duane B. Lakings · Pharmaceutical Sciences Encyclopedia · 2010
Abstract The discovery and development of a novel therapeutic agent requires scientific expertise from a number of different disciplines, an enormous amount of time, and money. Research studies conducted during the discovery phase in in vitro systems and in animal models can determine whether a discovery lead or group of leads. This article discusses some of the in vitro and in vivo assays employed by researchers during the drug discovery and developability assessment phases of the discovery and development processes.