Mining the Cambridge Structural Database for Bioisosteres
Colin R. Groom, Tjelvar S. G. Olsson, John W. Liebeschuetz, David A. Bardwell, Ian J. Bruno, Frank H. Allen · 2012
This chapter contains sections titled: Introduction The Cambridge Structural Database The Cambridge Structural Database System The Relevance of the CSD to Drug Discovery Assessing Bioisosteres: Conformational Aspects Assessing Bioisosteres: Nonbonded Interactions Finding Bioisosteres in the CSD: Scaffold Hopping and Fragment Linking A Case Study: Bioisosterism of 1H-Tetrazole and Carboxylic Acid Groups Conclusions References