Controlled Shape Deformations via Medial Profiles
Ghassan Hamarneh, Tim McInerney · Chalmers Publication Library (Chalmers University of Technology) · 2001
Robust, automatic segmentation and analysis of medical images requires powerful and flexible models of anatomical structures. We present a multiscale, medial-based approach to shape representation and controlled deformation in an effort to meet these requirements. We use medial-based profiles for shape representation, which follow the geometry of the structure and describe general, intuitive, and independent shape measures (length, orientation, and thickness). Controlled shape deformations (stretch, bend, and bulge) are obtained either as a result of applying deformation operators at certain locations and scales on the medial profiles, or by varying the weights of the main variation modes obtained from a hierarchical (multiscale) and regional (multi-location) principal component analysis of the medial profiles. We demonstrate the ability to produce controlled shape deformations on a medial-based representation of the corpus callosum. Furthermore, we present results of segmenting the corpus callosum in 2D mid-sagittal MRI slices of the brain.