Predicting the Polypharmacology of Drugs: Identifying New Uses through Chemoinformatics, Structural Informatics, and Molecular Modeling‐Based Approaches
Li Xie, Sarah Kinnings, Lei Xie, Philip E. Bourne · 2012
This chapter contains sections titled: Introduction The Concept of Polypharmacology and Its Relationship to Drug Resistance, Side Effects, and Drug Repositioning The Importance of Drug Repositioning in the Pharmaceutical Industry Chemical and Protein Structure-Based Approaches Molecular Activity Similarity-Based Methods Other Approaches through Data and Text Mining Conclusion References