Toxicogenomics Applied to Cardiovascular Toxicity
Thomas Thum, Jürgen T. Borlak · 2005
This chapter contains sections titled: Introduction Toxicogenomics Applied to Cardiovascular Toxicity Drug-induced Cardiac Arrhythmias Drug-induced Myocardial Apoptosis and Necrosis Drug-induced Cardiomyopathy and Myocardial Remodelling Drug-induced Myocarditis and Inflammation Drug-induced Effects on Cardiac Contractility Drug-induced Cardiac Hypertrophy Drug-induced Vascular Injury Environmental Pollution and Cardiotoxicity: Effect of Halogenated Aromatic Hydrocarbons Importance of Single Nucleotide Polymorphisms (SNPs) and Tissue-specific Drug Metabolism in Cardiovascular Drug Therapy Single Nucleotide Polymorphisms and Drug Treatment of Cardiovascular Diseases Tissue-specific Metabolism in Cardiovascular Tissues Conclusions References