Accurate 3D Modeling of Breast Deformation for Temporal Mammogram Registration
Dmitry B. Goldgof · 2008
In this research project, we have developed mathematical model of breast deformation to simulate breast compression during mammographic imaging. We have developed two types of mammogram registration methods: magnetic resonance imaging (MRI) guided registration and generic registration. Datasets have been constructed to validate the developed registrations methods. Mammogram registrations have been performed on concurrent mammograms using MRI guided and generic registration method, respectively. Also both registration methods have been applied onto temporal mammograms. Promising evaluation results demonstrate feasibility of the developed mammogram registration methods. The results also demonstrate that the developed registration methods would be very helpful in mammogram interpretation for improving accuracy of detection and diagnosis of breast cancer.