What Does an HTS File of the Future Look Like?
François Bertelli · 2012
This chapter contains sections titled: Introduction History of Compounds Collection for HTS Impact of High-Throughput Chemistry on Corporate Files Chemical Library Management The Concept of Drug-Likeness and the Lipinski Rules Quality versus Quantity The Emergence of the Subsets: Fragment, G-Protein-Coupled Receptor (GPCR), Ion Channel, Kinase, Protein–Protein Interaction, Chemogenomics, Library Of Pharmacologically Active Compounds (LOPAC), Central Nervous System (CNS), and Diversity Re-designing the Corporate File for the Future Future Routes for Hit Identification References