201 Structure guided novel lead molecules against ERK proteins: application of multiple docking and molecular dynamics studies
Sandeep Swargam, Dibyabhaba Pradhan, N. S. Pradeep, Kanipakam Hema, Vagolu Siva Krishna, Amineni Umamaheswari · Journal of Biomolecular Structure and Dynamics · 2015
Human extracellular regulated kinase (ERK1 and ERK2) proteins are serine/threonine protein-kinases; these two proteins having 88% sequence similarity and also the ATP binding site residues. ERKs ar...