INTERCRITERIA ANALYSIS FOR IDENTIFICATION OF ESCHERICHIA COLI FED-BATCH MATHEMATICAL MODEL
Tatiana Ilkova, Mitko Petrov · Materials, methods & technologies · 2015
Escherichia coli produces insulin, interferons, growth factors, exoand endoproducts, e.g. enzymes, etc. In this paper we present a new approach for multicriteria decision making – InterCriteria Analysis to mathematical modelling of a fermentation process. It is based on the apparatus of index matrices and intuitionistic fuzzy sets. The approach for multicriteria analysis makes it possible to compare certain criteria or estimated by them objects. In this paper we apply the ideas in an E. coli fed-batch laboratory process. We explore the basic dependencies between different criteria in fedbatch fermentation – biomass, substrate, oxygen and carbon dioxide. As a result, we develop structural and parametric identification of the process.